Results: ET patients showed significantly worse cognition, depression, anxiety, sleep and NMSS domains (p < 0.001), compared to controls, that negatively affected and predicted QoL. Both groups were divided into two subgroups of younger (45 years, 16 patients) groups, to investigate age-related differences. Subjects were evaluated by the Fahn-Tolosa-Marin Tremor Rating Scale, Non-Motor Symptoms Scale (NMSS), Montreal Cognitive Assessment, Hamilton Anxiety Rating Scale, Beck Depression Inventory, Pittsburgh Sleep quality Index, and the Short Form 36 Health Survey Questionnaire. Methods: Thirty ET patients were compared to 30 matched controls. This study aimed to investigate the clinical phenotype and impact of NMSs on QoL in Egyptian patients with ET. Elkady, Ahmed Elrassas, Hanan Hamid, Eman Elbalkimy, Mahmoud H.īackground: Identifying the clinical phenotypes of non-motor symptoms (NMSs) of essential tremor (ET) among different populations is necessary due to their impact on the quality of life (QoL). Truong, Mark Hallett, and Aasef Shaikh.2019 Articles Clinical Profile of Non-Motor Symptoms in Patients with Essential Tremor: Impact on Quality of Life and Age-Related Differences This article is part of the Special Issue "Tremor" edited by Daniel D. This relationship must be considered when interpreting change in clinical ratings, produced by disease or treatment. Transducer measures are logarithmically related to clinical ratings, as predicted by the Weber-Fechner law of psychophysics. Transducers and scales are presently viewed as complementary methods of quantifying tremor amplitude. Comprehensive anatomical and behavioral assessment of tremor with transducers is not clinically feasible. However, these advantages of transducers are mitigated by the considerable within-subject random variability in tremor amplitude, such that the smallest detectable statistically significant change in tremor amplitude is comparable for scales and transducers. The precision and accuracy of motion transducers exceed that of all clinical rating scales. Motion transducers are needed for an accurate determination of tremor frequency and for precise quantification of changes in amplitude and frequency over time. Motion transducers are often used in conjunction with surface electromyography to discern properties of tremor that are important diagnostically. Clinical rating scales are most useful when performing a comprehensive assessment of tremor severity (amplitude), anatomical distribution, activation conditions, and impact on activities of daily living and quality of life. Tremor can be characterized in terms of amplitude and frequency of oscillation, and these kinematic properties vary randomly and with activities of daily living. Tremor is an involuntary oscillatory movement of a body part. The purpose of this review is to characterize and compare validated clinical rating scales and transducers that are used in the clinical assessment of tremor disorders.
0 kommentar(er)
